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Class 12 Biology Objective In English Chapter – 5 Principles of Inheritance & Variation
1. The phenotypic ratio for F2 generation in Incomplete dominance is
( A ) 3 : 1
( B ) 2 : 2
( C ) 1 : 2 : 1
( D ) None of these
ANS-( C )
2. Sickle – cell anemia is related to which type of disease ?
( A ) Sex linked disease
( B ) Autosomal linked disease
( C ) Deficiency disease
( D ) Metabolic disease
ANS-( B )
3. The ratio of phenotypes in F2 of a monohybrid cross is :
( A ) 3 : 1
( B ) 1 : 2 : 1
( C ) 9 : 3 : 3 : 1
( D ) 2 : 1
ANS-( A )
4. A pure tall pea was crossed with a pure dwarf pea . All the plants of F1 were found to be tall . This is due to :
( A ) Dominance
( B ) Disappearance of factor for dwarfness in F1 generation
( C ) Segregation of factors
( D ) Co – ordination
ANS-( A )
5. Sickle cell anemia shows
( A ) Epistasis
( B ) Co – dominance
( C ) Pleiotrophy
( D ) Incomplete dominance
ANS-( C )
6. The trisomy of 21st chromosome causes
( A ) Kleinfelter’s syndrome
( B ) Turner’s Syndrome
( C ) Sickle cell Anemia
( D ) Down’s syndrome
ANS-( D )
7. ABO blood grouping in human beings cites the examples of
( A ) Incomplete dominance
( B ) Co – dominance
( C ) Multiple allelism
( D ) Both ( B ) and ( C )
ANS-( D )
8. Which of the following will not result in variation among siblings ?
( A ) Independent assortment
( B ) Crossing over
( C ) Linkage
( D ) Mutation
ANS-( C )
9. Chromosomal theory of inheritance was given by :
( A ) Morgan
( B ) Sutton & Boveri
( C ) Hugo de Vries
( D ) Mendel
ANS-( B )
10. Which of the following is not an example of recessive autosomal disease ?
( A ) Haemophilia
( B ) Cystic Fibrosis
( C ) Phenylketonuria
( D ) Sickle-cell Anemia
ANS-( A )
11. Mongolism in a genetic disorder caused by the presence of an extra chromosome number:
( A ) 20
( B ) 21
( C ) 17
( D ) 23
ANS-( B )
12. Kleinfelter’s syndrome is characterised by
( A ) XYY
( B ) XO
( C ) XXX
( D ) XXY
ANS-( D )
13. Grasshopper is an example of XO type of sex determination in which males have:
( A ) one X chromosome
( B ) no Y-chromosome
( C ) two X-chromosome
( D ) no X-chromosome
ANS-( A )
14. Father of a child is colourblind and mother is carrier for colourblindness,the possibility of the child being colourblind is:
( A ) 25 %
( B ) 50 %
( C ) 100 %
( D ) 75 %
ANS-( B )
15. Female’s with Turner’s syndrome have
( A ) small uterus
( B ) rudimentary ovaries
( C ) underdeveloped breasts
( D ) all of these
ANS-( D )
16 Trisohry is represented by
( A ) (2n – 1)
( B ) (2n – 2 )
( C ) (2n + 2)
( D ) (2n + 1)
ANS-( D )
17. A couple has six daughters. What is the possibility of their having a girl next time
( A ) 10 %
( B ) 50 %
( C ) 90 %
( D ) 100 %
ANS-( B )
18. What can be the blood group of offspring AB blood when group both? parents have
( A ) AB only
( B ) A, B & AB
( C ) A, B, AB & O
( D ) A & B only
ANS – ( B )
19. A normal vision female whose father is colour-blind marries a normal vision male What would be the probability of her sons and daughters to be colour blind?
( A ) 25 % sons colourblind and all daughters with phenotypically normal vision
( B ) 50 % sons colourblind and 50 % daughters normal.
( C ) 50 % sons colourblind and 50 % daughter colour blind.
( D ) Allsons normal and 50 % colourblind daughter
ANS-( B )
20. A family has 5 daughters. Probability of 6th child being boy will be:
( A ) 1 in 2
( B ) 1 in 5
( C ) 1 in 3
( D ) 1 in 6
ANS-( A )
21. A genotype AaBBCcDD can produce how many types of gametes?
( A ) 4
( B ) 3
( C ) 16
( D ) 64
ANS-( A )
22. In a dihybrid test cross the genotypic ratio of the progeny is:
( A ) 9: 3: 3: 1
( B ) 1: 1: 1: 1
( C ) 3: 1: 2: 1
( D ) 1: 7: 1
ANS-( B )
23. If mother has ‘ O ‘ blood group and child also has ‘ O ‘ group. What will be the blood group of Father?
( A ) O
( B ) A
( C ) B
( D ) AB
ANS-( A )
24. Child has blood group o ‘ and his father is’ B ‘ type. Then genotype of the father should be:
( A ) IBIB
( B ) IB IO
( C ) IA IB
( D ) lOIO
ANS-( B )
25. Antiserum used in testing blood groups has:
( A ) Antibody
( B ) Antigen
( C ) Leucocytes
( D ) None
ANS-( A )
26. Polygenic inheritance in plants like tobacco was first studied by:
( A ) Davenport
( B ) Nilsson-Ehle
( C ) Kolreuter
( D ) Galton
ANS-( C )
27. A recessive trait in Garden pea is
( A ) wrinkled seeds
( B ) tall stem
( C ) round seeds
( D ) coloured seeds coats
ANS-( A )
28. In complementary genes, the dihybrid ratio of 9: 3: 3: 1 is modified into
( A ) 9: 7
( B ) 12: 3: 1
( C ) 15: 1
( D ) 13: 3
ANS-( A )
29. Which blood groups are common in Man & Apes but absent in Monkey?
( A ) A and O
( B ) A and B
( C ) AB and O
( D ) B and AB
ANS-( B )
30. Number of barr bodies present in Turner’s syndrome is:
( A ) 0
( B ) 1
( C ) 2
( D ) 8
ANS-( A )
31. In an individual haploid number is 10. Its tetrasomic number will be:
( A ) 40
( B ) 14
( C ) 22
( D ) 44
ANS-( C )
32. A male grass hopper will have a sex complement of:
( A ) XY
( B ) XX
( C ) XO
( D ) YO
ANS-( C )
33. Individuals with blood group A has:
( A ) Antigen A, antibody B
( B ) Antigen B, antibody A
( C ) Antigen A, antibody b
( D ) Antigen A, no antibody
ANS-( C )
34. Phenomenon of one gene controlling several phenotypes is:
( A ) Epistasis
( B ) Pleiotropism
( C ) Co-dominance
( D ) Multiple allelism
ANS-( B )
35. The monohybrid genotypic ratio 1: 2 : 1 in F2 generation indicates:
( A ) Segregation
( B ) Independent assortment
( C ) Dominance
( D ) Incomplete dominance
ANS-( A )
36. Genes present on same locus having different expressions are called
( A ) Multiple allele
( B ) Polygene
( C ) Oncogene
( D ) Codominant gene
ANS-( A )
37. The human chromosome with highest and least number of genes are
( A ) Chromosome 21 and Y
( B ) Chromosome 1 and X
( C ) Chromosome 1 and Y
( D ) Chromosome X and Y
ANS-( C )
38. Sickle cell anaemia shows-
( A ) Epistrasis
( B ) Co – dominance
( C ) Pleiotropy
( D ) Incomplete dominance
ANS-( C )
39. The trisomy of 21st chromosome causes …
( A ) Klinefelter’s syndrome
( B ) Turner’s syndrome
( C ) Sickle cell anaemia
( D ) Down’s syndrome
ANS-( D )
40. A normal vision female whose father is colour – blind marries normal vision male What would be the probability of her sons and daughters to be colour blind ?
( A ) 25 % sons colour blind and all daughters with phenotypically normal vision
( B ) 50 % sons colour blind and 50 % daughter mormal
( C ) 50 % sons colour blind and 50 % daughter colour blind .
( D ) All sons normal and 50 % colour blind daughter
ANS-( B )
41. A child with blood group o ‘ has B blood group type father then the father has geno type of —
( A ) lOIO
( B ) IOIB
( C ) IBIB
( D ) IA IA
ANS-( B )
42. Lactose ( Lac ) operon is regulated by :
( A ) Lac repressor only
( B ) Lac repressor and CAP – CAMP complex
( C ) Lac repressor and c – GMP complex
( D ) CAP CAMP and CAP GMP complex
ANS-( B )
43. The distance between the genes is measured by :
( A ) angstrom
( B ) map unit
( C ) Dobson unit
( D ) millimeter
ANS-( B )
44. The percentage of ab gamete produced by AaBb parent will be
( A ) 25 %
( B ) 50 %
( C ) 75 %
( D ) 12.5 %
ANS-( A )
45. Which of the following is a test cross ?
( A ) TT x TT
( B ) Tt x Tt
( C ) tt x tt
( D ) Tt x tt
ANS-( D )
Class 12 Biology Objective In English Chapter – 5 Principles of Inheritance & Variation
46. Number of Autosomes present in Liver cells of a human female is :
( A ) 22 Autosomes
( B ) 22 pairs
( C ) 23 Autosome
( D ) 23 pairs
ANS-( B )
47. A person suffering from colour blindness can not recognise :
( A ) red & yellow colours
( B ) red & green colours
( C ) blue & green colours
( D ) None of these
ANS-( B )
48. In human blood group AB :
( A ) antibodies are present
( B ) antibodies are absent
( C ) antibody a is present
( D ) antibody b is present
ANS-( B )
49. Mendel proposed
( A ) Law of linkage
( B ) 10 % energy law
( C ) Laws of inheritance
( D ) none of these
ANS-( C )
50. Who is regarded as ‘ Father of Genetics
( A ) Mendel
( B ) Morgan
( C ) Lamarek
( D ) De Vries
ANS-( A )
51. The number of different type of gametes produced from a plant with genotype AaBbcc is :
( A ) 2
( B ) 8
( C ) 4
( D ) 16
ANS-( A )
52. How many types of gametes are expected from the organism with genotype AABBCC ?
( A ) One
( B ) Two
( C ) Four
( D ) Eight
ANS-( A )
53. A haploid set of all the genes present in a gamete is called
( A ) Genotype
( B ) Phenotype
( C ) Genome
( D ) Linkage group
ANS-( C )
54.Number of characters studied by Mendel in Pea was ?
( A ) 5
( B ) 7
( C ) 6
( D ) 4
ANS-( B )
55. The The genotypic ratio of a monohybrid cross will be
( A ) 3 : 1
( B ) 1 : 1
( C ) 1 : 2 : 1
( D ) 2 : 1
ANS-( C )
56. Mendel’s law of segregation is based upon the F ratio of :
( A ) 1 : 2
( B ) 9 : 3 : 3 : 1
( C ) 1 : 2 : 1
( D ) 3 : 1
ANS-( D )
57 Genes do not occur in pairs in :
( A ) Zygote
( B ) Somatic cell
( C ) Endosperm cells
( D ) Gametes
ANS-( D )
58. Segregation of genes take place during
( A ) Metaphase
( B ) Anaphase
( C ) Prophase
( D ) Embryo formation
ANS-( B )
59. A cross between hybrid and a parent is known as :
( A ) Monohybrid cross
( B ) Back cross
( C ) Test cross
( D ) Reciprocal cross
ANS-( C )
60. cross between offspring and recessive parent is
( A ) Monohybrid cross
( B ) Back cross
( C ) Test cross
( D ) Reciprocal cross
ANS-( C )
61. Common test to find genotype of hybrid is by :
( A ) Studying sexual behaviour of F1 progeny
( B ) Crossing F1 individuals with recessive parents
( C ) Crossing one F2 progeny.with male parents
( D ) Crossing one F2 progeny with female parent
ANS-( B )
62. Segregation of genes occurs in :
( A ) Embryo formation
( B ) Anaphase I
( C ) Anaphase
( D ) Metapliase
ANS-( B )
63. Offspring produced from a cross between two pure individuals differering in one set of characters is called :
( A ) Monohybrid
( B ) Mutant
( C ) Polyploid
( D) Variant
ANS-( A )
64. Test Cross is performed to known the genotype . It is a cross between
( A ) F1 hybrid with dominant parent
( B ) F1 hybrid with recessive parent
( C ) Two F1 hybrids
( D ) Two F2 hybrids
ANS-( B )
65. A cross between hybrid and either of any parent is called :
( A ) test cross
( B ) reciprocal cross
( C ) Monohybrid cross
( D ) back cross
ANS-( D )
66. To see the effect of sex on inheritance , Mendal performed :
( A ) test cross
( B ) out cross
( C ) reciprocal cross
( D ) sib cross
ANS-( C )
67. A cross between F hybrid with the dominant parent is called :
( A ) Test cross
( B ) out cross
( C ) back cross
( D ) reverse cross
ANS-( B )
68. A dominant trait in the following is :
( A ) Colourblindness
( B ) Night blindness
( C ) RH
( D ) Albinism
ANS-( C )
69. Independent assortment of Mendal was :
( A ) Monohybrid cross
( B ) Dihybrid cross
( C ) Incomplete dominance
( D ) Back cross
ANS-( B )
70. IF Mendel has considered eighth trait in pea , which law would have failed ?
( A ) Law of segregation
( B ) Law of Purity of gametes
( C ) Law of independent
( D ) Law of dominance
ANS-( C )
Class 12 Biology Objective In English Chapter – 5 Principles of Inheritance & Variation
71. An exception to Mendelian Law of independent assortment is :
( A ) Crossing over
( B ) Incomplete dominance
( C ) Segregation
( D ) Linkage
ANS-( D )
72. Who modified Mendel’s postulates as Mendel’s laws ?
( A ) Correns
( B ) Tschermark
( C ) Hugo de Vries
( D ) Morgan
ANS-( A )
73. In incomplete dominance in F2 generation :
( A ) ratio of phenotype is 3 : 1
( B ) ratio of genotype is 3 : 1
( C ) both ( A ) and ( B )
( D ) phenotypic ratio corresponds to genotypic ratio
ANS-( D )
74. A tall plant on selfing produce tall and dwarf both What are the probabilities that first offspring will be ?
( A ) tall
( B ) dwarf
( C ) equal chance
( D ) data not sufficient
ANS-( A )
75. Offspring of which of the following crosses are all phenotypically alike ?
( A ) Dd x Dd
( B ) Dd x dd
( C ) DD x Dd
( D ) Ww x Ww
ANS-( C )
76. A test cross of AaBbCC produces how many phenotypes ?
( A ) 16
( B ) 12
( C ) 8
( D ) 4
ANS-( D )
77. Which one of the following individuals can produce 16 different gametes ?
( A ) Aa Bb cc Dd
( B ) Aa Bb cc DD Ee Ff
( C ) Aa Bb Cc dd EE FF
( D ) Aa Bb Cc DD Ee FF
ANS-( B )
78. Which is pure hybrid in the following ?
( A ) Rrtt
( B ) TTrr
( C ) TtRr
( D ) TTRR
ANS-( C )
79. Which one of the following crosses shows 3 : 1 ratio ?
( A ) AaBb x AaBb
( B ) aabb × AABb
( C ) Aabb × Aabb
( D ) AaBb x aabb
ANS-( C )
80. ABO blood group in humans is an example of
( A ) Polygenic inheritance
( B ) Multifactor inheritance
( C ) Pleiotrople gene
( D ) Multiple alleles
ANS-( D )
81. Genotype of A – group father and of O – group child would be :
( A ) IA IA
( B ) IA i
( C ) IA I B
( D ) ii
ANS-( B )
82. An O – group child can not have parents of blood groups :
( A ) B and B
( B ) A and B
( C ) O and O
( D ) AB and O
ANS-( D )
83. A recessive trait in Garden Pea is :
( A ) Tall stem
( B ) Coloured flower
( C ) Wrinkled seed
( D ) Inflated pod
ANS-( C )
84. Dihybrid test cross is :
( A ) 1 : 1 : 1 : 1
( B ) 1 : 1
( C ) 9 : 3 : 3 : 1
( D ) 15 : 1
ANS-( A )
85. A couple has two girls . The probability of a third girl baby is :
( A ) 100 %
( B ) 50 %
( C ) 25 %
( D ) 12.5 %
ANS-( B )
86. Genes present on the same locus but having different expressions are :
( A ) Multiple alleles
( B ) Polygenes
( C ) Oncogenes
( D ) Co – dominants
ANS-( A )
87. How many kinds of gemetes will be produced by AA Bb cc genotype ?
( A ) Two
( B ) Four
( C ) Six
( D ) Nine
ANS-( A )
88. Phenotypic ratio of monohybrid F1 progeny of an incomplete dominance is
( A ) 1 : 1 : 1 : 1
( B ) 1 : 2 : 1
( C ) 3 : 1
( D ) 2 : 1 : 2
ANS-( B )
89. Sickle cell anaemia shows :
( A ) Epistasis
( B ) Co – dominance
( C ) Pleiotropy
( D ) Incomplete dominance
ANS-( C )
90. G.J. Mendel was :
( A ) British monk
( B ) Australian monik
( C ) Austrian monk
( D ) German scientist
ANS-( C )
91. Ultimate source of variation is :
( A ) Mitosis
( B ) Hybridisation
( C ) Fertilization
( D ) Mutations
ANS-( D )
92. A monohybrid cross produced tall and dwarf Pea plants in ratio of 3 : 1. Their genotypes would be :
( A ) TT × Tt
( B ) Tt x Tt
( C ) TT x tt
( D ) Tt x H
ANS-( B )
93 Individuals with blood group A has
( A ) Antigen A , antibody B
( B ) Antigen B , antibody A
( C ) Antigen A , antibody b
( D ) Antigen A , no antibody
ANS-( C )
94. Mendel’s law of segregation applicable to :
( A ) Monohybrid cross
( B ) Hybrid cross
( C ) Hybrid but Monohybrid cross
( D ) Homologous pairs between chromosome
ANS-( D )
